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LORBRENA® (lorlatinib) is a prescription medicine that is used to treat people with non-small cell lung cancer (NSCLC)

  • that is caused by an abnormal anaplastic lymphoma kinase (ALK) gene, and
  • that has spread to other parts of the body, and
  • who have taken the medicine:
    • alectinib, or ceritinib, or
    • both crizotinib and at least 1 other medicine to treat NSCLC that is caused by the ALK gene, and
  • that is no longer responding to these treatments.

It is not known if LORBRENA is safe and effective in children.

The effectiveness of LORBRENA is based on a study that measured tumor response rate and duration of response. There is an ongoing study to find out how LORBRENA works over a longer period of time.

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A Next-Generation Therapy

The ALK+ NSCLC treatment landscape is continuously evolving, and LORBRENA® is one of the latest ALK inhibitor therapies. It is a prescription medicine for people living with anaplastic lymphoma kinase (ALK)+ non-small cell lung cancer (NSCLC) that has spread to other parts of the body and their NSCLC is no longer responding to alectinib or ceritinib, or crizotinib and at least 1 other ALK inhibitor medicine.

LORBRENA is available in a 100-mg strength tablet and a 25-mg strength tablet.

 

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