Indication Tooltip

LORBRENA® (lorlatinib) is a prescription medicine that is used to treat people with non-small cell lung cancer (NSCLC)

  • that is caused by an abnormal anaplastic lymphoma kinase (ALK) gene, and
  • that has spread to other parts of the body, and
  • who have taken the medicine:
    • alectinib, or ceritinib, or
    • both crizotinib and at least 1 other medicine to treat NSCLC that is caused by the ALK gene, and
  • that is no longer responding to these treatments.

It is not known if LORBRENA is safe and effective in children.

The effectiveness of LORBRENA is based on a study that measured tumor response rate and duration of response. There is an ongoing study to find out how LORBRENA works over a longer period of time.



Hear from real patients about their diagnosis and treatment journey, what they’ve learned, and how they’re coping with their disease.

Gina and Jeff were asked to share their personal stories about LORBRENA®. All content was accurate at the time of filming in October 2019 and may have changed. Individual results may vary.

Gina’s Story

Gina is a wife, mother of two, and retired nurse from Memphis, Tennessee. Learn more about her family’s experience following her diagnosis, treatment journey, and how she and her family work through daily challenges of living with lung cancer.

Read what Gina had to say about how she stays positive during her treatment:

Before I was diagnosed, I read something about how if two men look through a window, one will see mud while the other sees stars.

My family and I loved that saying and we decided that we were going to start looking at the stars in our lives. Every time I am facing a difficult situation, I ask myself, 'What’s it going to be, mud or stars?' And I say, 'It’s going to be stars. Stars all the way.'

When I was diagnosed, my family and I could look at this whole journey and see ourselves as victims, or we could make the very best of it and choose to help and inspire the most people that we can. 

jeff’s Story

Jeff is a retired firefighter and full-time farmer from Piqua, Ohio. Learn about how Jeff and his wife, Rhonda, have managed their lives following his diagnosis, his treatment journey, and what they're doing to help advocate for lung cancer patients around the world.

Read what Jeff's wife, Rhonda, had to say about what they look forward to:

When Jeff was diagnosed, we decided to take a trip for our upcoming anniversary. We didn’t know how many anniversaries we would have left together, so we decided to rent a condo on the beach in Destin, Florida.

At one point during the trip, I remember thinking to myself that I wanted to have a photo. We walked down to the beach, and I had Jeff stand in the sand while I drew a big heart around him. I put the year, and how many years we were married.

Because Jeff has responded to his treatments, this trip became a tradition for us. We have gone back every year since then and have taken the same picture in the same spot, drawing the same heart in the sand. It gives us hope and reason to look forward. 

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