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LORBRENA may cause some side effects that you did not experience while on other ALK inhibitor medicines. These side effects include increased cholesterol and/or triglycerides, hallucinations, seizures, and changes in mood, memory, thinking, or speech.
If you experience side effects, know that with your doctor's guidance, there may be ways to help manage them.
It may be helpful to have an open conversation with your family or caregiver about the potential side effects of LORBRENA. They may be able to help you recognize any changes and can help you share them with your doctor.
If these problems are severe, your healthcare provider may need to have you stop taking LORBRENA.
–Females who are able to become pregnant should use effective non-hormonal birth control during treatment with LORBRENA and for at least 6 months after the final dose of LORBRENA. Birth control pills (oral contraceptives) and other hormonal forms of birth control may not be effective if used during treatment with LORBRENA. Talk to your healthcare provider about birth control choices that are right for you during this time.
–Males who have female partners who are able to become pregnant should use effective birth control during treatment with LORBRENA and for at least 3 months after the final dose of LORBRENA.
Tell your healthcare provider about all the medicines you take, including prescription medicines, over-the-counter medicines, vitamins, and herbal supplements.
Do not take LORBRENA if you take certain other medicines called strong CYP3A inducers. Ask your healthcare provider for a list of these medicines if you are not sure.
LORBRENA may cause decreased fertility in males. In males, this could affect your ability to father a child. Talk to your healthcare provider if you have concerns about fertility.
These are not all of the possible side effects of LORBRENA. For more information, ask your healthcare provider or pharmacist.
Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
LORBRENA is a prescription medicine that is used to treat people with non-small cell lung cancer (NSCLC)
It is not known if LORBRENA is safe and effective in children.
The effectiveness of LORBRENA is based on a study that measured tumor response rate and duration of response. There is an ongoing study to find out how LORBRENA works over a longer period of time.